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Center or periphery? Modeling the effects of focal adhesion placement during cell spreading
Focal adhesions are often observed at the cell’s periphery. We provide an explanation for this observation using a system-level mathematical model of a cell interacting with a two-dimensional substrate. The model describes the biological cell as a hypoelastic continuum material whose behavior is cou...
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Publicado no: | PLoS One |
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Main Authors: | , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Public Library of Science
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5291721/ https://ncbi.nlm.nih.gov/pubmed/28158263 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0171430 |
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