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Center or periphery? Modeling the effects of focal adhesion placement during cell spreading

Focal adhesions are often observed at the cell’s periphery. We provide an explanation for this observation using a system-level mathematical model of a cell interacting with a two-dimensional substrate. The model describes the biological cell as a hypoelastic continuum material whose behavior is cou...

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Bibliographic Details
Published in:PLoS One
Main Authors: Stolarska, Magdalena A., Rammohan, Aravind R.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5291721/
https://ncbi.nlm.nih.gov/pubmed/28158263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0171430
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