The Calcineurin Target, Crz1, Functions in Azole Tolerance but Is Not Required for Virulence of Candida albicans

In Candida albicans, calcineurin is essential for virulence and survival during membrane perturbation by azoles. Crz1 is a proposed downstream target of calcineurin based on studies of Saccharomyces cerevisiae. However, the in vitro phenotypes of C. albicans crz1/crz1 and calcineurin mutants differ...

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Detalles Bibliográficos

Publicado en:	Infect Immun
Principais autores:	Onyewu, Chiatogu, Wormley, Floyd L., Perfect, John R., Heitman, Joseph
Formato:	Artigo
Idioma:	Inglês
Publicado:	American Society for Microbiology (ASM) 2004
Assuntos:	Fungal and Parasitic Infections
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC529171/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15557662/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.72.12.7330-7333.2004
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