Severity of Human African Trypanosomiasis in East Africa Is Associated with Geographic Location, Parasite Genotype, and Host Inflammatory Cytokine Response Profile

The mechanisms underlying virulence in human African trypanosomiasis are poorly understood, although studies with experimental mice suggest that unregulated host inflammatory responses are associated with disease severity. We identified two trypanosomiasis foci with dramatically different disease vi...

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Autors principals: MacLean, Lorna, Chisi, John E., Odiit, Martin, Gibson, Wendy C., Ferris, Vanessa, Picozzi, Kim, Sternberg, Jeremy M.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2004
Matèries:
Fungal and Parasitic Infections
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC529158/
https://ncbi.nlm.nih.gov/pubmed/15557627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.12.7040-7044.2004
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