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Severity of Human African Trypanosomiasis in East Africa Is Associated with Geographic Location, Parasite Genotype, and Host Inflammatory Cytokine Response Profile

The mechanisms underlying virulence in human African trypanosomiasis are poorly understood, although studies with experimental mice suggest that unregulated host inflammatory responses are associated with disease severity. We identified two trypanosomiasis foci with dramatically different disease vi...

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Detalhes bibliográficos
Main Authors: MacLean, Lorna, Chisi, John E., Odiit, Martin, Gibson, Wendy C., Ferris, Vanessa, Picozzi, Kim, Sternberg, Jeremy M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC529158/
https://ncbi.nlm.nih.gov/pubmed/15557627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.12.7040-7044.2004
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