l-Arginine Availability Modulates Local Nitric Oxide Production and Parasite Killing in Experimental Trypanosomiasis

Nitric oxide (NO) is an important effector molecule of the immune system in eliminating numerous pathogens. Peritoneal macrophages from Trypanosoma brucei brucei-infected mice express type II NO synthase (NOS-II), produce NO, and kill parasites in the presence of l-arginine in vitro. Nevertheless, p...

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Auteurs principaux: Gobert, Alain P., Daulouede, Sylvie, Lepoivre, Michel, Boucher, Jean Luc, Bouteille, Bernard, Buguet, Alain, Cespuglio, Raymond, Veyret, Bernard, Vincendeau, Philippe
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2000
Sujets:
Fungal and Parasitic Infections
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC98402/
https://ncbi.nlm.nih.gov/pubmed/10899869
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