Serum Arginase, a Biomarker of Treatment Efficacy in Human African Trypanosomiasis

Arginase serum levels were increased in human African trypanosomiasis patients and returned to control values after treatment. Arginase hydrolyzes l-arginine to l-ornithine, which is essential for parasite growth. Moreover, l-arginine depletion impairs immune functions. Arginase may be considered as...

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Detalhes bibliográficos
Main Authors: Nzoumbou-Boko, Romaric, Dethoua, Mariette, Gabriel, Fréderic, Buguet, Alain, Cespuglio, Raymond, Courtois, Pierrette, Daulouède, Sylvie, Bouteille, Bernard, Ngampo, Stéphane, Mpandzou, Ghislain, Semballa, Silla, Vincendeau, Philippe
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Parasitology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3697696/
https://ncbi.nlm.nih.gov/pubmed/23554207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.03371-12
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