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Structure activity relationship and modeling studies of inhibitors of lysine specific demethylase 1
Post-translational modifications of histone play important roles in gene transcription. Aberrant methylation of histone lysine sidechains have been often found in cancer. Lysine specific demethylase 1 (LSD1), which can demethylate histone H3 lysine 4 (H3K4) and other proteins, has recently been foun...
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| Yayımlandı: | PLoS One |
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| Asıl Yazarlar: | , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Public Library of Science
2017
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5291514/ https://ncbi.nlm.nih.gov/pubmed/28158205 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0170301 |
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