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Structural insight into inhibitors of flavin adenine dinucleotide-dependent lysine demethylases

Until 2004, many researchers believed that protein methylation in eukaryotic cells was an irreversible reaction. However, the discovery of lysine-specific demethylase 1 in 2004 drastically changed this view and the concept of chromatin regulation. Since then, the enzymes responsible for lysine demet...

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Bibliographic Details
Published in:Epigenetics
Main Authors: Niwa, Hideaki, Umehara, Takashi
Format: Artigo
Language:Inglês
Published: Taylor & Francis 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5453194/
https://ncbi.nlm.nih.gov/pubmed/28277979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15592294.2017.1290032
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