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A 10S galectin-3–U1 snRNP complex assembles into active spliceosomes

In previous studies, we reported that fractionation of HeLa cell nuclear extracts on glycerol gradients revealed an endogenous ∼10S particle that contained galectin-3 and U1 snRNP and this particle was sufficient to load the galectin polypeptide onto a pre-mRNA substrate. We now document that this i...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Haudek, Kevin C., Voss, Patricia G., Wang, John L., Patterson, Ronald J.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
RNA
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5291251/
https://ncbi.nlm.nih.gov/pubmed/27105840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw303
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