Selective release of muscle-specific, extracellular microRNAs during myogenic differentiation

MyomiRs are muscle-specific microRNAs (miRNAs) that regulate myoblast proliferation and differentiation. Extracellular myomiRs (ex-myomiRs) are highly enriched in the serum of Duchenne Muscular Dystrophy (DMD) patients and dystrophic mouse models and consequently have potential as disease biomarkers...

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Publicado en:Hum Mol Genet
Autores principales: Coenen-Stass, Anna M.L., Betts, Corinne A., Lee, Yi F., Mäger, Imre, Turunen, Mikko P., EL Andaloussi, Samir, Morgan, Jennifer E., Wood, Matthew J.A., Roberts, Thomas C.
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2016
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Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5291232/
https://ncbi.nlm.nih.gov/pubmed/27466195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddw237
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