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Extracellular microRNAs exhibit sequence-dependent stability and cellular release kinetics
Multiple studies have described extracellular microRNAs (ex-miRNAs) as being remarkably stable despite the hostile extracellular environment, when stored at 4ºC or lower. Here we show that many ex-miRNAs are rapidly degraded when incubated at 37ºC in the presence of serum (thereby simulating physiol...
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| Publicado no: | RNA Biol |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6546368/ https://ncbi.nlm.nih.gov/pubmed/30836828 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2019.1582956 |
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