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Efficient genome replication of hepatitis B virus using adenovirus vector: a compact pregenomic RNA-expression unit
The complicated replication mechanisms of hepatitis B virus (HBV) have impeded HBV studies and anti-HBV therapy development as well. Herein we report efficient genome replication of HBV applying adenovirus vectors (AdVs) showing high transduction efficiency. Even in primary hepatocytes derived from...
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| Udgivet i: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5291108/ https://ncbi.nlm.nih.gov/pubmed/28157182 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep41851 |
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