Adenovirus vectors lacking virus-associated RNA expression enhance shRNA activity to suppress hepatitis C virus replication

First-generation adenovirus vectors (FG AdVs) expressing short-hairpin RNA (shRNA) effectively downregulate the expressions of target genes. However, this vector, in fact, expresses not only the transgene product, but also virus-associated RNAs (VA RNAs) that disturb cellular RNAi machinery. We have...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Pei, Zheng, Shi, Guoli, Kondo, Saki, Ito, Masahiko, Maekawa, Aya, Suzuki, Mariko, Saito, Izumu, Suzuki, Tetsuro, Kanegae, Yumi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3868971/
https://ncbi.nlm.nih.gov/pubmed/24356586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep03575
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados