Maternal Sall4 Is Indispensable for Epigenetic Maturation of Mouse Oocytes

Sall4 (Splat-like 4) plays important roles in maintaining pluripotency of embryonic stem cells and in various developmental processes. Here, we find that Sall4 is highly expressed in oocytes and early embryos. To investigate the roles of SALL4 in oogenesis, we generated Sall4 maternal specific knock...

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Veröffentlicht in:J Biol Chem
Hauptverfasser: Xu, Kai, Chen, Xia, Yang, Hui, Xu, Yiwen, He, Yuanlin, Wang, Chenfei, Huang, Hua, Liu, Baodong, Liu, Wenqiang, Li, Jingyi, Kou, Xiaochen, Zhao, Yanhong, Zhao, Kun, Zhang, Linfeng, Hou, Zhenzhen, Wang, Hong, Wang, Hailin, Li, Jing, Fan, Hengyu, Wang, Fengchao, Gao, Yawei, Zhang, Yong, Chen, Jiayu, Gao, Shaorong
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2017
Schlagworte:
Developmental Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5290953/
https://ncbi.nlm.nih.gov/pubmed/28031467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.767061
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