Naïve Induced Pluripotent Stem Cells Generated From β-Thalassemia Fibroblasts Allow Efficient Gene Correction With CRISPR/Cas9

Conventional primed human embryonic stem cells and induced pluripotent stem cells (iPSCs) exhibit molecular and biological characteristics distinct from pluripotent stem cells in the naïve state. Although naïve pluripotent stem cells show much higher levels of self-renewal ability and multidifferent...

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Detalhes bibliográficos
Publicado no:Stem Cells Transl Med
Main Authors: Yang, Yuanyuan, Zhang, Xiaobai, Yi, Li, Hou, Zhenzhen, Chen, Jiayu, Kou, Xiaochen, Zhao, Yanhong, Wang, Hong, Sun, Xiao-Fang, Jiang, Cizhong, Wang, Yixuan, Gao, Shaorong
Formato: Artigo
Idioma:Inglês
Publicado em: AlphaMed Press 2016
Assuntos:
Pluripotent Stem Cells
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4704878/
https://ncbi.nlm.nih.gov/pubmed/26676643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5966/sctm.2015-0157
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