Naïve Induced Pluripotent Stem Cells Generated From β-Thalassemia Fibroblasts Allow Efficient Gene Correction With CRISPR/Cas9

Conventional primed human embryonic stem cells and induced pluripotent stem cells (iPSCs) exhibit molecular and biological characteristics distinct from pluripotent stem cells in the naïve state. Although naïve pluripotent stem cells show much higher levels of self-renewal ability and multidifferent...

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Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Stem Cells Transl Med
Päätekijät: Yang, Yuanyuan, Zhang, Xiaobai, Yi, Li, Hou, Zhenzhen, Chen, Jiayu, Kou, Xiaochen, Zhao, Yanhong, Wang, Hong, Sun, Xiao-Fang, Jiang, Cizhong, Wang, Yixuan, Gao, Shaorong
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: AlphaMed Press 2016
Aiheet:
Pluripotent Stem Cells
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4704878/
https://ncbi.nlm.nih.gov/pubmed/26676643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5966/sctm.2015-0157
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