Signal Transducer and Activator of Transcription 1 Plays a Pivotal Role in RET/PTC3 Oncogene-induced Expression of Indoleamine 2,3-Dioxygenase 1

Indoleamine 2,3-dioxygenase 1 (IDO1) is a single chain oxidoreductase that catalyzes tryptophan degradation to kynurenine. In cancer, it exerts an immunosuppressive function as part of an acquired mechanism of immune escape. Recently, we demonstrated that IDO1 expression is significantly higher in a...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :J Biol Chem
Главные авторы: Moretti, Sonia, Menicali, Elisa, Nucci, Nicole, Voce, Pasquale, Colella, Renato, Melillo, Rosa Marina, Liotti, Federica, Morelli, Silvia, Fallarino, Francesca, Macchiarulo, Antonio, Santoro, Massimo, Avenia, Nicola, Puxeddu, Efisio
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2017
Предметы:
Signal Transduction
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5290952/
https://ncbi.nlm.nih.gov/pubmed/27994058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.745448
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы