Intracellular Signal Transduction and Modification of the Tumor Microenvironment Induced by RET/PTCs in Papillary Thyroid Carcinoma

RET gene rearrangements (RET/PTCs) represent together with BRAF point mutations the two major groups of mutations involved in papillary thyroid carcinoma (PTC) initiation and progression. In this review, we will examine the mechanisms involved in RET/PTC-induced thyroid cell transformation. In detai...

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Detalhes bibliográficos
Main Authors: Menicali, Elisa, Moretti, Sonia, Voce, Pasquale, Romagnoli, Serena, Avenia, Nicola, Puxeddu, Efisio
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Research Foundation 2012
Assuntos:
Endocrinology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3357465/
https://ncbi.nlm.nih.gov/pubmed/22661970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2012.00067
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