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YAP enhances the pro‐proliferative transcriptional activity of mutant p53 proteins
Mutant p53 proteins are present in more than half of human cancers. Yes‐associated protein (YAP) is a key transcriptional regulator controlling organ growth, tissue homeostasis, and cancer. Here, we report that these two determinants of human malignancy share common transcriptional signatures. YAP p...
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| Publicado no: | EMBO Rep |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5290815/ https://ncbi.nlm.nih.gov/pubmed/26691213 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201540488 |
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