YAP enhances the pro‐proliferative transcriptional activity of mutant p53 proteins

Mutant p53 proteins are present in more than half of human cancers. Yes‐associated protein (YAP) is a key transcriptional regulator controlling organ growth, tissue homeostasis, and cancer. Here, we report that these two determinants of human malignancy share common transcriptional signatures. YAP p...

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Enregistré dans:
Détails bibliographiques
Publié dans:EMBO Rep
Auteurs principaux: Di Agostino, Silvia, Sorrentino, Giovanni, Ingallina, Eleonora, Valenti, Fabio, Ferraiuolo, Maria, Bicciato, Silvio, Piazza, Silvano, Strano, Sabrina, Del Sal, Giannino, Blandino, Giovanni
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2015
Sujets:
Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5290815/
https://ncbi.nlm.nih.gov/pubmed/26691213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201540488
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