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Mutant p53 Protein and the Hippo Transducers YAP and TAZ: A Critical Oncogenic Node in Human Cancers

p53 protein is a well-known tumor suppressor factor that regulates cellular homeostasis. As it has several and key functions exerted, p53 is known as “the guardian of the genome” and either loss of function or gain of function mutations in the TP53 coding protein sequence are involved in cancer onse...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Ferraiuolo, Maria, Verduci, Lorena, Blandino, Giovanni, Strano, Sabrina
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5454874/
https://ncbi.nlm.nih.gov/pubmed/28467351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18050961
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