Binding to Nonmethylated CpG DNA Is Essential for Target Recognition, Transactivation, and Myeloid Transformation by an MLL Oncoprotein

The MLL gene is a frequent target for leukemia-associated chromosomal translocations that generate dominant-acting chimeric oncoproteins. These invariably contain the amino-terminal 1,400 residues of MLL fused with one of a variety of over 30 distinct nuclear or cytoplasmic partner proteins. Despite...

Descripció completa

Dades bibliogràfiques

Publicat a:	Mol Cell Biol
Autors principals:	Ayton, Paul M., Chen, Everett H., Cleary, Michael L.
Format:	Artigo
Idioma:	Inglês
Publicat:	Taylor & Francis 2004
Matèries:	Cell Growth and Development
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC529055/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15542854/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.24.23.10470-10478.2004
Etiquetes:	Afegir etiqueta Sense etiquetes, Sigues el primer a etiquetar aquest registre!