Fingolimod alters the transcriptome profile of circulating CD4+ cells in multiple sclerosis

Multiple sclerosis is a demyelinating disease affecting the central nervous system. T cells are known to contribute to this immune-mediated condition. Fingolimod modulates sphingosine-1-phosphate receptors, thereby preventing the egress of lymphocytes, especially CCR7-expressing CD8+ and CD4+ T cell...

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Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Friess, Jörg, Hecker, Michael, Roch, Luisa, Koczan, Dirk, Fitzner, Brit, Angerer, Ines Charlotte, Schröder, Ina, Flechtner, Kristin, Thiesen, Hans-Jürgen, Winkelmann, Alexander, Zettl, Uwe Klaus
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2017
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5290459/
https://ncbi.nlm.nih.gov/pubmed/28155899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep42087
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