Fingolimod alters the transcriptome profile of circulating CD4+ cells in multiple sclerosis

Multiple sclerosis is a demyelinating disease affecting the central nervous system. T cells are known to contribute to this immune-mediated condition. Fingolimod modulates sphingosine-1-phosphate receptors, thereby preventing the egress of lymphocytes, especially CCR7-expressing CD8+ and CD4+ T cell...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Sci Rep
Päätekijät: Friess, Jörg, Hecker, Michael, Roch, Luisa, Koczan, Dirk, Fitzner, Brit, Angerer, Ines Charlotte, Schröder, Ina, Flechtner, Kristin, Thiesen, Hans-Jürgen, Winkelmann, Alexander, Zettl, Uwe Klaus
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group 2017
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5290459/
https://ncbi.nlm.nih.gov/pubmed/28155899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep42087
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