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High-Density Peptide Microarray Analysis of IgG Autoantibody Reactivities in Serum and Cerebrospinal Fluid of Multiple Sclerosis Patients

Intrathecal immunoglobulin G (IgG) synthesis and oligoclonal IgG bands in cerebrospinal fluid (CSF) are hallmarks of multiple sclerosis (MS), but the antigen specificities remain enigmatic. Our study is the first investigating the autoantibody repertoire in paired serum and CSF samples from patients...

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Detalhes bibliográficos
Publicado no:Mol Cell Proteomics
Main Authors: Hecker, Michael, Fitzner, Brit, Wendt, Matthias, Lorenz, Peter, Flechtner, Kristin, Steinbeck, Felix, Schröder, Ina, Thiesen, Hans-Jürgen, Zettl, Uwe Klaus
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4824861/
https://ncbi.nlm.nih.gov/pubmed/26831522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M115.051664
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