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Principles and Practical Considerations for the Analysis of Disease-Associated Alternative Splicing Events Using the Gateway Cloning-Based Minigene Vectors pDESTsplice and pSpliceExpress

Splicing is an important RNA processing step. Genetic variations can alter the splicing process and thereby contribute to the development of various diseases. Alterations of the splicing pattern can be examined by gene expression analyses, by computational tools for predicting the effects of genetic...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Putscher, Elena, Hecker, Michael, Fitzner, Brit, Lorenz, Peter, Zettl, Uwe Klaus
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8152502/
https://ncbi.nlm.nih.gov/pubmed/34068052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22105154
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