Deficiency in SNM1 Abolishes an Early Mitotic Checkpoint Induced by Spindle Stress

Spindle poisons represent an important class of anticancer drugs that act by interfering with microtubule polymerization and dynamics and thereby induce mitotic checkpoints and apoptosis. Here we show that mammalian SNM1 functions in an early mitotic stress checkpoint that is distinct from the well-...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Mol Cell Biol
Prif Awduron: Akhter, Shamima, Richie, Christopher T., Deng, Jian Min, Brey, Eric, Zhang, Xiaoshan, Patrick, Charles, Behringer, Richard R., Legerski, Randy J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Taylor & Francis 2004
Pynciau:
DNA Dynamics and Chromosome Structure
Mynediad Ar-lein:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC529044/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15542852/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.24.23.10448-10455.2004
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