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SWAP-70 Regulates c-kit-Induced Mast Cell Activation, Cell-Cell Adhesion, and Migration
SWAP-70, an unusual phosphatidylinositol-3-kinase-dependent protein that interacts with the RhoGTPase Rac, is highly expressed in mast cells. Cultured bone marrow mast cells (BMMC) from SWAP-70(−/−) mice are reduced in FcɛRI-triggered degranulation. This report describes the hitherto-unknown role of...
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| Главные авторы: | , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Microbiology
2004
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC529030/ https://ncbi.nlm.nih.gov/pubmed/15542837 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.23.10277-10288.2004 |
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