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SWAP-70 deficiency causes high-affinity plasma cell generation despite impaired germinal center formation

Germinal centers (GCs) are lymphoid tissue structures central to the generation of long-lived, high-affinity, antibody-forming B cells. However, induction, maintenance, and regulation of GCs are not sufficiently understood. The F-actin–binding, Rac-interacting protein SWAP-70 is strongly expressed i...

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Detalhes bibliográficos
Main Authors: Quemeneur, Laurence, Angeli, Veronique, Chopin, Michael, Jessberger, Rolf
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2254552/
https://ncbi.nlm.nih.gov/pubmed/18094331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-07-102822
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