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SWAP-70 deficiency causes high-affinity plasma cell generation despite impaired germinal center formation
Germinal centers (GCs) are lymphoid tissue structures central to the generation of long-lived, high-affinity, antibody-forming B cells. However, induction, maintenance, and regulation of GCs are not sufficiently understood. The F-actin–binding, Rac-interacting protein SWAP-70 is strongly expressed i...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society of Hematology
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2254552/ https://ncbi.nlm.nih.gov/pubmed/18094331 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-07-102822 |
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