Nuclear Speckle-Associated Protein Pnn/DRS Binds to the Transcriptional Corepressor CtBP and Relieves CtBP- Mediated Repression of the E-Cadherin Gene

Previously, we have shown that pinin/DRS (Pnn), a 140-kDa nuclear and cell adhesion-related phosphoprotein, is involved in the regulation of cell adhesion and modulation of the activity of multiple tumor suppressor genes. In the nucleus Pnn is concentrated in the “nuclear speckles,” zones of accumul...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Mol Cell Biol
Prif Awduron: Alpatov, Roman, Munguba, Gustavo Costa, Caton, Paul, Joo, Jeong Hoon, Shi, Yang, Shi, Yujiang, Hunt, Marguerite E., Sugrue, Stephen P.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Taylor & Francis 2004
Pynciau:
Transcriptional Regulation
Mynediad Ar-lein:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC529029/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15542832/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.24.23.10223-10235.2004
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