Nuclear Speckle-Associated Protein Pnn/DRS Binds to the Transcriptional Corepressor CtBP and Relieves CtBP- Mediated Repression of the E-Cadherin Gene

Previously, we have shown that pinin/DRS (Pnn), a 140-kDa nuclear and cell adhesion-related phosphoprotein, is involved in the regulation of cell adhesion and modulation of the activity of multiple tumor suppressor genes. In the nucleus Pnn is concentrated in the “nuclear speckles,” zones of accumul...

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Main Authors: Alpatov, Roman, Munguba, Gustavo Costa, Caton, Paul, Joo, Jeong Hoon, Shi, Yang, Shi, Yujiang, Hunt, Marguerite E., Sugrue, Stephen P.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2004
主題:
Transcriptional Regulation
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC529029/
https://ncbi.nlm.nih.gov/pubmed/15542832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.23.10223-10235.2004
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