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Corepressor CtBP and Nuclear Speckle Protein Pnn/DRS Differentially Modulate Transcription and Splicing of the E-Cadherin Gene

CtBP is a transcriptional corepressor with tumorigenic potential that targets the promoter of the tumor suppressor gene E-cadherin. Pnn/DRS (Pnn) is a “nuclear speckle”-associated protein involved in mRNA processing as well as transcriptional regulation of E-cadherin via its binding to CtBP. Here, w...

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Detalhes bibliográficos
Main Authors: Alpatov, Roman, Shi, Yujiang, Munguba, Gustavo C., Moghimi, Babak, Joo, Jeong-Hoon, Bungert, Jorg, Sugrue, Stephen P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2258767/
https://ncbi.nlm.nih.gov/pubmed/18086895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00421-07
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