Portal protein functions akin to a DNA-sensor that couples genome-packaging to icosahedral capsid maturation

Tailed bacteriophages and herpesviruses assemble infectious particles via an empty precursor capsid (or ‘procapsid') built by multiple copies of coat and scaffolding protein and by one dodecameric portal protein. Genome packaging triggers rearrangement of the coat protein and release of scaffol...

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Bibliografiske detaljer
Udgivet i:Nat Commun
Main Authors: Lokareddy, Ravi K., Sankhala, Rajeshwer S., Roy, Ankoor, Afonine, Pavel V., Motwani, Tina, Teschke, Carolyn M., Parent, Kristin N., Cingolani, Gino
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5290284/
https://ncbi.nlm.nih.gov/pubmed/28134243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms14310
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