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Breaking Symmetry in Viral Icosahedral Capsids as Seen through the Lenses of X-ray Crystallography and Cryo-Electron Microscopy

The majority of viruses on Earth form capsids built by multiple copies of one or more types of a coat protein arranged with 532 symmetry, generating an icosahedral shell. This highly repetitive structure is ideal to closely pack identical protein subunits and to enclose the nucleic acid genomes. How...

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Detalhes bibliográficos
Publicado no:Viruses
Main Authors: Parent, Kristin N., Schrad, Jason R., Cingolani, Gino
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5850374/
https://ncbi.nlm.nih.gov/pubmed/29414851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v10020067
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