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Structure of Human PIR1, an Atypical Dual-Specificity Phosphatase
[Image: see text] PIR1 is an atypical dual-specificity phosphatase (DSP) that dephosphorylates RNA with a higher specificity than phosphoproteins. Here we report the atomic structure of a catalytically inactive mutant (C152S) of the human PIR1 phosphatase core (PIR1-core, residues 29–205), refined a...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American
Chemical Society
2014
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| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3985963/ https://ncbi.nlm.nih.gov/pubmed/24447265 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi401240x |
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