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Influence of Escherichia coli chaperone DnaK on protein immunogenicity

The production of anti‐drug antibodies can impact significantly upon the safety and efficacy of biotherapeutics. It is known that various factors, including aggregation and the presence of process‐related impurities, can modify and augment the immunogenic potential of proteins. The purpose of the in...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Immunology
Päätekijät: Ratanji, Kirsty D., Derrick, Jeremy P., Kimber, Ian, Thorpe, Robin, Wadhwa, Meenu, Dearman, Rebecca J.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: John Wiley and Sons Inc. 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5290234/
https://ncbi.nlm.nih.gov/pubmed/27859059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12689
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