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Differential role of hematopoietic and non-hematopoietic cell types in the regulation of NK cell tolerance and responsiveness()

Many NK cells express inhibitory receptors that bind self MHC class I molecules and prevent killing of self-cells, while enabling killing of MHC I-deficient cells. But tolerance also occurs for NK cells that lack inhibitory receptors for self MHC I, and for all NK cells in MHC I-deficient animals. I...

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Veröffentlicht in:J Immunol
Hauptverfasser: Shifrin, Nataliya Tovbis, Kissiov, Djem U., Ardolino, Michele, Joncker, Nathalie T., Raulet, David H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5289891/
https://ncbi.nlm.nih.gov/pubmed/27798146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1402447
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