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Cytokine therapy restores antitumor responses of NK cells rendered anergic in MHC I-deficient tumors

Recent extraordinary advances in cancer immunotherapy rely primarily on marshaling T cell responses. Here we discuss how NK cell responses can be amplified. We find that MHC I-deficient tumors induce anergy of NK cells but that cytokine therapy restores NK cell activity and increases the survival of...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Oncoimmunology
Egile Nagusiak: Ardolino, Michele, Raulet, David H
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Taylor & Francis 2015
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4760323/
https://ncbi.nlm.nih.gov/pubmed/26942049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2014.1002725
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