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Cytokine therapy restores antitumor responses of NK cells rendered anergic in MHC I-deficient tumors
Recent extraordinary advances in cancer immunotherapy rely primarily on marshaling T cell responses. Here we discuss how NK cell responses can be amplified. We find that MHC I-deficient tumors induce anergy of NK cells but that cytokine therapy restores NK cell activity and increases the survival of...
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| Udgivet i: | Oncoimmunology |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Taylor & Francis
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4760323/ https://ncbi.nlm.nih.gov/pubmed/26942049 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2014.1002725 |
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