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Continuous treatment with FTS confers resistance to apoptosis and affects autophagy
High percentage of human cancers involves alteration or mutation in Ras proteins, including the most aggressive malignancies, such as lung, colon and pancreatic cancers. FTS (Salirasib) is a farnesylcysteine mimetic, which acts as a functional Ras inhibitor, and was shown to exert anti-tumorigenic e...
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| Publicat a: | PLoS One |
|---|---|
| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Public Library of Science
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5289601/ https://ncbi.nlm.nih.gov/pubmed/28151959 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0171351 |
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