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Identification of small molecules that disrupt vacuolar function in the pathogen Candida albicans

The fungal vacuole is a large acidified organelle that performs a variety of cellular functions. At least a sub-set of these functions are crucial for pathogenic species of fungi, such as Candida albicans, to survive within and invade mammalian tissue as mutants with severe defects in vacuolar bioge...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Tournu, Helene, Carroll, Jennifer, Latimer, Brian, Dragoi, Ana-Maria, Dykes, Samantha, Cardelli, James, Peters, Tracy L., Eberle, Karen E., Palmer, Glen E.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5289544/
https://ncbi.nlm.nih.gov/pubmed/28151949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0171145
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