Identification of small molecules that disrupt vacuolar function in the pathogen Candida albicans

The fungal vacuole is a large acidified organelle that performs a variety of cellular functions. At least a sub-set of these functions are crucial for pathogenic species of fungi, such as Candida albicans, to survive within and invade mammalian tissue as mutants with severe defects in vacuolar bioge...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:PLoS One
Prif Awduron: Tournu, Helene, Carroll, Jennifer, Latimer, Brian, Dragoi, Ana-Maria, Dykes, Samantha, Cardelli, James, Peters, Tracy L., Eberle, Karen E., Palmer, Glen E.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2017
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5289544/
https://ncbi.nlm.nih.gov/pubmed/28151949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0171145
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