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Effect of pregabalin administration upon reperfusion in a rat model of hyperglycemic stroke: Mechanistic insights associated with high-mobility group box 1

Hyperglycemia, which reduces the efficacy of treatments and worsens clinical outcomes, is common in stroke. Ability of pregabalin to reduce neuroexcitotoxicity may provide protection against stroke, even under hyperglycemia. We investigated its protective effect against hyperglycemic stroke and its...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Song, Young, Jun, Ji-Hae, Shin, Eun-Jung, Kwak, Young-Lan, Shin, Jeon-Soo, Shim, Jae-Kwang
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5289503/
https://ncbi.nlm.nih.gov/pubmed/28152042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0171147
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