Protective Effect of Ethyl Pyruvate against Myocardial Ischemia Reperfusion Injury through Regulations of ROS-Related NLRP3 Inflammasome Activation

Emerging evidence indicates the pronounced role of inflammasome activation linked to reactive oxygen species (ROS) in the sterile inflammatory response triggered by ischemia/reperfusion (I/R) injury. Ethyl pyruvate (EP) is an antioxidant and conveys myocardial protection against I/R injury, while th...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Oxid Med Cell Longev
Main Authors: Jun, Ji Hae, Shim, Jae-Kwang, Oh, Ju Eun, Shin, Eun-Jung, Shin, Eunah, Kwak, Young-Lan
Format: Artigo
Jezik:Inglês
Izdano: Hindawi 2019
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6343167/
https://ncbi.nlm.nih.gov/pubmed/30728885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/4264580
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