Antigenic characterization of the human immunodeficiency virus (HIV-1) envelope glycoprotein precursor incorporated into nanodiscs

The entry of human immunodeficiency virus (HIV-1) into host cells is mediated by the viral envelope glycoproteins (Envs), which are derived by the proteolytic cleavage of a trimeric gp160 Env precursor. The mature Env trimer is a major target for entry inhibitors and vaccine-induced neutralizing ant...

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Veröffentlicht in:PLoS One
Hauptverfasser: Witt, Kristen C., Castillo-Menendez, Luis, Ding, Haitao, Espy, Nicole, Zhang, Shijian, Kappes, John C., Sodroski, Joseph
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2017
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5289478/
https://ncbi.nlm.nih.gov/pubmed/28151945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0170672
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