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The biodistribution of 5-[(18)F]fluoropyrazinamide in Mycobacterium tuberculosis-infected mice determined by positron emission tomography
5-[(18)F]F-pyrazinamide (5-[(18)F]F-PZA), a radiotracer analog of the first-line tuberculosis drug pyrazinamide (PZA), was employed to determine the biodistribution of PZA using PET imaging and ex vivo analysis. 5-[(18)F]F-PZA was synthesized in 60 min using a halide exchange reaction. The overall d...
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| 出版年: | PLoS One |
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| 主要な著者: | , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Public Library of Science
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5289470/ https://ncbi.nlm.nih.gov/pubmed/28151985 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0170871 |
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