Superoxide dismutase/catalase mimetic EUK-134 prevents diaphragm muscle weakness in monocrotalin-induced pulmonary hypertension

Patients with pulmonary hypertension (PH) suffer from inspiratory insufficiency, which has been associated with intrinsic contractile dysfunction in diaphragm muscle. Here, we examined the role of redox stress in PH-induced diaphragm weakness by using the novel antioxidant, EUK-134. Male Wistar rats...

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Detaylı Bibliyografya
Yayımlandı:PLoS One
Asıl Yazarlar: Himori, Koichi, Abe, Masami, Tatebayashi, Daisuke, Lee, Jaesik, Westerblad, Håkan, Lanner, Johanna T., Yamada, Takashi
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2017
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5289453/
https://ncbi.nlm.nih.gov/pubmed/28152009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0169146
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