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Endothelial targeting of liposomes encapsulating SOD/Catalase mimetic EUK-134 alleviates acute pulmonary inflammation

Production of excessive levels of reactive oxygen species (ROS) in the vascular endothelium is a common pathogenic pathway in many dangerous conditions, including acute lung injury, ischemia-reperfusion, and inflammation. Ineffective delivery of antioxidants to the endothelium limits their utility f...

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Detalhes bibliográficos
Publicado no:J Control Release
Main Authors: Howard, Melissa D., Greineder, Colin F., Hood, Elizabeth D., Muzykantov, Vladimir R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4593476/
https://ncbi.nlm.nih.gov/pubmed/24412573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2013.12.035
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