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Microarrays of small molecules embedded in biodegradable polymers for use in mammalian cell-based screens
We developed a microarray-based system for screening small molecules in mammalian cells. This system is compatible with image-based screens and requires fewer than 100 cells per compound. Each compound is impregnated in a 200-μm-diameter disc composed of biodegradable poly-(d),(l)-lactide/glycolide...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
2004
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC528944/ https://ncbi.nlm.nih.gov/pubmed/15534212 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0404425101 |
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