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Microarrays of small molecules embedded in biodegradable polymers for use in mammalian cell-based screens

We developed a microarray-based system for screening small molecules in mammalian cells. This system is compatible with image-based screens and requires fewer than 100 cells per compound. Each compound is impregnated in a 200-μm-diameter disc composed of biodegradable poly-(d),(l)-lactide/glycolide...

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Detalhes bibliográficos
Main Authors: Bailey, Steve N., Sabatini, David M., Stockwell, Brent R.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC528944/
https://ncbi.nlm.nih.gov/pubmed/15534212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0404425101
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