A Comparative Analysis of Drug-Induced Hepatotoxicity in Clinically Relevant Situations

Drug-induced toxicity is a significant problem in clinical care. A key problem here is a general understanding of the molecular mechanisms accompanying the transition from desired drug effects to adverse events following administration of either therapeutic or toxic doses, in particular within a pat...

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Detalhes bibliográficos
Publicado no:PLoS Comput Biol
Main Authors: Thiel, Christoph, Cordes, Henrik, Fabbri, Lorenzo, Aschmann, Hélène Eloise, Baier, Vanessa, Smit, Ines, Atkinson, Francis, Blank, Lars Mathias, Kuepfer, Lars
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5289425/
https://ncbi.nlm.nih.gov/pubmed/28151932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1005280
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